Publications


  1. Kurhade SE, Weiner JD, Gao FP, Farrell MP. Functionalized High Mannose-Specific Lectins for the Discovery of Type I Mannosidase Inhibitors. Angew Chem Int Ed Engl. 2021 May 25;60(22):12313-12318. doi: 10.1002/anie.202101249. Epub 2021 Apr 26. PMID: 33728787; PMCID: PMC8131250. (available on 2022-05-25) DOI: 10.1002/anie.202101249

  2. Alhammad YMO, Kashipathy MM, Roy A, Gagné JP, McDonald P, Gao P, Nonfoux L, Battaile KP, Johnson DK, Holmstrom ED, Poirier GG, Lovell S, Fehr AR. The SARS-CoV-2 conserved macrodomain is a highly efficient ADP-ribosylhydrolase enzyme. bioRxiv [Preprint]. 2020 May 12:2020.05.11.089375. doi: 10.1101/2020.05.11.089375. Update in: J Virol. 2021 Jan 13;95(3): PMID: 32511412; PMCID: PMC7263559.

  3. Alhammad YMO, Kashipathy MM, Roy A, Gagné JP, McDonald P, Gao P, Nonfoux L, Battaile KP, Johnson DK, Holmstrom ED, Poirier GG, Lovell S, Fehr AR. The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase. J Virol. 2021 Jan 13;95(3):e01969-20. doi: 10.1128/JVI.01969-20. PMID: 33158944; PMCID: PMC7925111.

  4. Montoya NA, Barr KE, Morales SV, Umana JE, Ny C, Roth RE, Reyes EJ, Kirchhoff BC, Hartman ER, Higgins LL, Nichol KM, Morais ARC, Allgeier AM, Gao P, Picking WD, Corbin DR, Shiflett MB. Protein Stabilization and Delivery: A Case Study of Invasion Plasmid Antigen D Adsorbed on Porous Silica. Langmuir. 2020 Dec 1;36(47):14276-14287. doi: 10.1021/acs.langmuir.0c02400. Epub 2020 Oct 23. PMID: 33095588.   - Journal Cover -

  5. Lan L, Xing M, Kashipathy M, Douglas J, Gao P, Battaile K, Hanzlik R, Lovell S, Xu L. Crystal and solution structures of human oncoprotein Musashi-2 N-terminal RNA recognition motif 1. Proteins. 2020 Apr;88(4):573-583. doi: 10.1002/prot.25836. Epub 2019 Oct 29. PMID: 31603583; PMCID: PMC7079100.

  6. Benson DR, Lovell S, Mehzabeen N, Galeva N, Cooper A, Gao P, Battaile KP, Zhu H. Crystal structures of the naturally fused CS and cytochrome b5 reductase (b5R) domains of Ncb5or reveal an expanded CS fold, extensive CS-b5R interactions and productive binding of the NAD(P)+ nicotinamide ring. Acta Crystallogr D Struct Biol. 2019 Jul 1;75(Pt 7):628-638. doi: 10.1107/S205979831900754X. Epub 2019 Jun 26. PMID: 31282472; PMCID: PMC6718094.

  7. Lan L, Liu H, Smith AR, Appelman C, Yu J, Larsen S, Marquez RT, Wu X, Liu FY, Gao P, Gowthaman R, Karanicolas J, De Guzman RN, Rogers S, Aubé J, Neufeld KL, Xu L. Natural product derivative Gossypolone inhibits Musashi family of RNA-binding proteins. BMC Cancer. 2018 Aug 10;18(1):809. doi: 10.1186/s12885-018-4704-z. PMID: 30097032; PMCID: PMC6086024.

  8. Lan, L., Xing, M., Douglas J.T., Gao, P., Hanzlik R.P., Xu, L. (2017)  Human oncoprotein Musashi-2 N-terminal RNA recognition motif backbone assignment and identification of RNA-binding pocket. Oncotarget 8(63):106587-106597.  PMID:  29290973  PMCID:  PMC573975

  9. Yu, J., Lan, L., Lewin, S.J., Rogers, S.A., Roy, A., Wu, X., Gao, P., Karanicolas, J., Aubé, J., Sun, B., Xu, L. (2017)  Identification of novel small molecule Beclin 1 mimetics activating autophagy.  Oncotarget  8(31):51355-51369. doi: 10.18632/oncotarget.17977. eCollection 2017 Aug 1. PMCID: PMC5584254

  10. Obayashi, E., Luna, R.E., Nagata, T., Martin-Marcos, P., Hiraishi, H., Singh, C.R., Erzberger, J.P., Zhang, F., Arthanari, H., Morris, J., Pellarin, R., Moore, C., Harmon, I., Papadopoulos, E., Yoshida, H., Nasr, M.L., Unzai, S., Thompson, B., Aubé, E., Hustak, S., Stengel, F., Dagraca, E., Ananbandam, A., Gao, P., Urano, T., Hinnebusch, A.G., Wagner, G., Asano, K. (2017) Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5.  Cell Rep. 18(11):2651-2663. doi: 10.1016/j.celrep.2017.02.052.  PMCID: PMC5382721

  11. McNiff, M.L., Haynes, E.P., Dixit, N., Gao, F.P., Laurence, J.S. (2016) Thioredoxin fusion construct enables high-yield production of soluble, active matrix metalloproteinase-8 (MMP-8) in Escherichia coli. Protein Expr. Purif. 122:64-71.  PMCID: PMC5137367

  12. Wahome, N., Cooper, A., Thapa, P., Choudhari, S., Gao, F.P., Volkin, D.B., Middaugh, C.R. (2016) Production of well-characterized virus-like particles in an Escherichia coli-based expression platform for preclinical vaccine assessments. Methods Mol. Biol. 1404:437-57. PMID: 27076315  [PubMed - in process]

  13. Lan, L., Appelman, C., Smith, A.R., Yu, J., Larsen, S., Marquez, R.T., Liu, H., Wu, X., Gao, P., Roy, A., Anbanandam, A., Gowthaman, R., Karanicolas, J., De Guzman, R.N., Rogers, S., Aubé, J., Ji, M., Cohen, R.S., Neufeld, K.L., Xu, L. (2015) Natural product (-)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1. Mol. Oncol. 2015 Aug;9(7):1406-20. doi: 10.1016/j.molonc.2015.03.014. Epub 2015 Apr 10.  PMCID: PMC4523432

  14. Chen, C., Shrestha, R., Jia, K., Gao, P.F., Geisbrecht, B.V., Bossmann, S.H., Shi, J., Li, P. (2015) Characterization of Dye-decolorizing Peroxidase (DyP) from Thermomonospora curvata Reveals Unique Catalytic Properties of A-type DyPs. J. Biol. Chem. 290(38):23447-63. PMCID: PMC4645587

  15. Wu, X., Lan, L., Wilson, D.M., Marquez, R.T., Tsao, W.C., Gao, P., Roy, A., Turner, B.A., McDonald, P., Tunge, J.A., Rogers, S.A., Dixon, D.A., Aubé, J., Xu, L.(2015) Identification and validation of novel small molecule disruptors of HuR-mRNA interaction. ACS Chem. Biol. 10(6):1476-84.  PMCID: PMC4631057

  16. Murray, D.T., Li, C., Gao, F.P., Qin, H., Cross, T.A., (2014) Membrane protein structural validation by oriented sample solid-state NMR: diacylglycerol kinase.  Biophys. J. 106(8):1559-69.  PMCID: PMC4008839

  17. Thomas, J.C., O’Hara, J.M., Hu, L., Gao, F.P., Joshi, S.B., Volkin, D.B., Brey, R.N., Fang, J., Karanicolas, J.*, Mantis, N.J., Middaugh, C.R. (2013) Effect of single-point mutations on the stability and immunogenicity of a recombinant ricin A chain subunit vaccine antigen. Hum. Vaccin. Immunother. 9(4): 1-9.  PMCID: PMC3903890